Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration
نویسندگان
چکیده
منابع مشابه
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration.
Cone phototransduction and survival of cones in the human macula is essential for color vision and for visual acuity. Progressive cone degeneration in age-related macular degeneration, Stargardt disease, and recessive cone dystrophies is a major cause of blindness. Thyroid hormone (TH) signaling, which regulates cell proliferation, differentiation, and apoptosis, plays a central role in cone op...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2014
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1317041111